Teste Repositóri
2014-01-01
Resultados de pesquisa
Foram encontrados 1.778 registos.
BACKGROUND: In previous randomized studies levosimendan improved hemodynamics and clinical course, with a still unclear effect on prognosis. There are, however, few data regarding its effects when used in daily practice.
AIMS: We evaluated the clinical effectiveness and safety of levosimendan in the treatment of acute systolic heart failure (SHF) in daily practice conditions.
METHODS: In this prospective, multicenter, nonrandomized trial, a continuous infusion of levosimendan (0.05 microg/kg/min-0.2 microg/kg/min) was administered for 24 hours. An optional loading dose of 12 microg/kg over 10 minutes was used. The primary combined endpoint of clinical effectiveness (as defined by a eight-variable clinical score) and safety (defined by the absence of serious adverse events) was assessed at 24 hours after the beginning of treatment; a ...
The prevalence, complexity, clinical importance, heterogeneity and unpredictability of inherited cardiovascular diseases make the development of inherited cardiovascular disease centers an inevitability, with the ultimate goal of reducing the morbidity and mortality associated with these conditions. An inherited cardiovascular disease center may be seen as a subunit of a cardiology department, with health professionals specializing in these types of disorders, organized to provide excellence in all related areas, including diagnosis, treatment, followup, prevention, risk stratification and prognosis. Among its objectives are the development of action protocols and the creation of databases that enable patients to be included in national and international research networks. To achieve these objectives these centers should include functi...
The pathogenesis of bronchopulmonary dysplasia (BPD) is clearly multifactorial. Specific pathogenic risk factors are prematurity, respiratory distress, oxygen supplementation, mechanical ventilation (MV), inflammation, patent ductus arteriosus (PDA), etc.
AIM: To evaluate BPD prevalence and to identify risk factors for BPD in five Portuguese Neonatal Intensive Care Units in order to develop better practices the management of these newborns.
MATERIAL AND METHODS: 256 very low birth weight infants with gestational age (GA) <30 weeks and/or birthweight (BW) <1250 g admitted in five Portuguese NICUs, between 2004 and 2006 were studied. A protocol was filled in based on clinical information registered in the hospital charts. BPD was defined as oxygen dependency at 36 weeks of postconceptional age.
RESULTS: BPD prevalence was 12.9% (33/25...
Introdução: Este estudo teve como objectivo determinar os principais sintomas percepcionados
pelos doentes com doença pulmonar obstrutiva crónica (DPOC) numa coorte de doentes que
participaram num grande ensaio clínico, que avaliou o tiotrópio e que decorreu em Portugal.
População e métodos: A caracterização dos sintomas, no momento de avaliação basal dos doentes
foi efectuada através do recurso a um questionário padronizado. Os doentes foram inquiridos
quanto aos principais sintomas que tinham levado ao diagnóstico e também quanto ao sintoma
actual mais problemático.
Resultados: Os resultados foram obtidos de 298 doentes, maioritariamente masculinos (95%),
que apresentavam, uma média (desvio padrão) de volume expiratório forçado no primeiro
segundo basal de 1,1 (0,4) L (40,6 [13.3] % do valor preditivo), uma duração média da ...
Background: Nephrolithiasis has been associated with hypertension, obesity and
diabetes Mellitus. The prevalence of adverse cardiovascular outcomes among kidney
stone formers (KSF) is unknown.
Methods: We examined the IV Portuguese National Health Survey for documenting
possible associations between nephrolithiasis, cardiovascular diseases, diabetes and obesity in the Portuguese adult population.
Results: We obtained 23,349 questionnaires from individuals with ≥ 15 year-old. The
prevalence of kidney stone disease was 7.3%. The prevalence of hypertension was
higher among KSF when compared with the general population (50.4% vs. 30.2%; p
< 0,001). Age and obesity significantly increase the risk for nephrolithiasis. After
adjusting for age and body mass index, KSF have higher prevalence of hypertension
(odds-ratio: 1.841; 95% CI:...
A suspeita ecográfica de uma anomalia fetal é motivo de grande ansiedade para os pais que perguntam qual a causa e o prognóstico da situação. O objectivo deste trabalho foi avaliar o diálogo médico-pais em 183 casos de anomalias do tracto urinário de diagnóstico ecográfico pré-natal e o processo vivido pelos pais desde a notícia da anomalia até ao nascimento.
Este grupo inclui casos muito diversos nos quais é difícil estabelecer o prognóstico mas a notícia vai desencadear nos pais a reacção a um filho doente, pelo que é importante determinar quem e como se fala a estes pais.
O nascimento de um bebé com anomalias é a perda súbita do filho que se desejava. No nosso grupo, uma grande percentagem de mães referiu ter sentido choque, desorientação, culpa, angústia, pavor, pânico e perturbações do sono ou alimentares. O facto de o diagnóst...
