Teste Repositóri
2014-01-01
Resultados de pesquisa
Foram encontrados 190 registos.
Dissertação de mestrado, Ciências Biomédicas, Departamento de Ciências Biomédicas e Biomedicina, Universidade do Algarve, 2013
Osteoarthritis (OA) is a whole-joint disease believed to onset after articular cartilage
damage and accompanied by tissue inflammation, abnormal bone formation and extracellular
matrix (ECM) mineralization. Gla-rich protein (GRP), the latest discovered vitamin Kdependent
protein (VKDP), was shown to accumulate in mouse and sturgeon cartilage, and
sites of skin and vascular calcification in human. Therefore, we investigated the possible
involvement of GRP with OA development. An osteoarthritic and control samples human
biobank was collected and used for the comparative analysis of GRP patterning at
transcriptional and translational levels. Two novel GRP alternative spliced transcripts were
unveiled in human (GRP-F5 and F6), yet GRP-F1, corresponding to the full-length protein,
was shown to be the predominant variant in articula...
Dissertação de mestrado, Ciências Farmacêuticas, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 2017
Several activities are ensured by dockers increase occupational exposure to several risk factors. being one of them the fungal burden from the load. In this study we aim at characterizing fungal contamination in one warehouse that storage sugar cane from a ship, and also in one crane cabinet that unload the same sugar cane from the ship. Air samples were collected from the warehouse and from inside the crane cabinet. An outdoor sample was also collected, from each sampling site, and regarding as reference. Sampling volume was selected depending in the contamination expected and the air samples were collect through an impaction method in a flow rate of 140 L/min onto malt extract agar (MEA) supplemented with chloramphenicol (0.05%), using the Millipore air Tester (Millipore). Surfaces samples from the warehouse were collected by swabbin...
Fungal contamination in composting facilities has been associated with increased respiratory and skin pathologies among compost workers. In this study we aim to characterize the fungal contamination caused by Aspergillus genera within a totally indoor composting plant located in Portugal. Air samples of 50L were collected from 6 sampling sites through an impaction method. Surfaces samples were collected by swabbing the surfaces of the same indoor sites. Pre-treatment and waste screw were the sampling sites of the analyzed composting plant with the highest Aspergillus load in the air. Globally, the genus Aspergillus presented the highest prevalence both in the air from (90.6%), and surfaces from the same sampling sites (60.8%). The results obtained in this study claim the attention to the need of further research regarding the fungal co...
Vários são os fatores de risco presentes no ambiente que podem afetar a saúde humana e influenciar a
qualidade de vida. Os fatores podem ser de natureza física, química e biológica e ainda psicossociais. O
estudo destes fatores de risco deverá ser realizado de forma detalhada e com uma abordagem multidisciplinar, permitindo o reconhecimento do impacto que estes fatores podem representar para a saúde humana. O grupo de investigação em Ambiente e Saúde da Escola Superior de Tecnologia da Saúde de Lisboa, além de pretender contribuir para a promoção da cultura científica na instituição, apresenta outros objetivos específicos relacionados com as suas linhas de investigação, designadamente: estudar em detalhe os fatores de risco presentes no ambiente e que podem colocar em causa a saúde humana; contribuir para o conhecimento no que concer...
RESUMO - Os trabalhadores dos ginásios com piscinas apresentam maior prevalência de lesões
fúngicas, como a Tinea pedis e a onicomicose, devido às características intrínsecas da sua
actividade profissional, pois apresentam mais horas por dia de exposição à contaminação
fúngica das superfícies. Esta situação verifica-se não só por serem os que mais frequentam os
locais possíveis de estarem contaminados, como é o caso de balneários, vestiários e zona
envolvente às piscinas, mas também porque algumas das actividades desenvolvidas são
realizadas com os pés descalços. Além disso, a utilização de roupa sintética e de calçado
ocluso, que retêm a sudação excessiva, favorece o desenvolvimento fúngico.
Constituiu objectivo deste trabalho conhecer o risco de infecção e/ou lesão (Tinea pedis
e onicomicose) nos trabalhadores dos ginásios c...
O presente estudo tem por objectivo a análise da
percepção das estratégias de coping, da qualidade de vida e da resiliência
familiar numa amostra composta por pessoas portadoras de
Paramiloidose (grupo 1) e por pessoas não portadoras de Paramiloidose
(grupo 2). A amostra clínica (N=30) foi recolhida a partir do Centro de
Estudos e Apoio à Paramiloidose, enquanto a amostra do grupo de
comparação (N=34) foi recolhida junto da população geral. Os
instrumentos utilizados foram as Escalas de avaliação pessoal orientadas
para a crise em família (F-COPES – McCubbin, Larsen & Olson, 1981
cit. Olson et al., 1985, versão NUSIAF – Sistémica, 2007), o inventário
Qualidade de Vida (QV – Olson & Barnes, 1982, cit. Olson et al., 1985,
versão NUSIAF – Sistémica, 2007) e o Questionário de Forças Familiares
(QFF – Melo & Alarcão, 2007). Foram também uti...
The production of MVOC by fungi has been taken into account especially from the viewpoint of indoor pollution with microorganisms but the relevance of fungal metabolites in working environments has not been sufficiently studied. The purpose of this study was to assess exposure to MVOCs in a waste-handling unit. It was used Multirae equipment (RAE Systems) to measured MVOCs concentration with a 10.6 eV lamps. The measurements were done near workers nose and during the normal activities. All measurements were done continuously and had the duration of 5 minutes at least. It was consider the higher value obtained in each measurement. In addition, for knowing fungi contamination, five air samples of 50 litres were collected through impaction method at 140 L/minute, at one meter tall, on to malt extract agar with the antibiotic chloramphenic...
Animal confinement tends to increase the overall microbial load in the production environment caused by high amounts of feed and organic residuals (manure and wastewater) present in those environments. The number of animais and the handling and management required to work in these settings also contribute to enhance that microbial ioad. Animal housing typically exposes workers to substantial concentrations of bioaerosols, such as fungi and their metabolites. Therefore, agricultural workers, and especially pig and poultry farmers, are at increased risk of occupational respiratory diseases. Exposure to bioaerosols in poultries and swines may vary depending upon the stage of the animals' growth, density, manure management procedures, litter type and used floor coverage, among others. Gathering temporal information about the quantity and t...
