Teste Repositóri
2014-01-01
Resultados de pesquisa
Foram encontrados 54 registos.
Tese de doutoramento, Ciências Biotecnológicas (Engenharia Bioquímica), Faculdade de Ciências e Tecnologia, Univ. do Algarve, 2011
Tese dout., Biologia - Fisiologia Animal, Universidade do Algarve, 2007
An acute exposure of two vanadate solutions—
metavanadate and decavanadate—containing different vanadate oligomers, induces different patterns of subcellular
vanadium distribution in blood plasma, red blood cells (RBC), and cardiac muscle subcellular fractions of the fish Sparus
aurata (gilthead seabream). The highest amount of vanadium was found in blood plasma 1 h after (5 mM) intravenous vanadate administration (295 € 64 and 383 € 104 lg V/g dry tissue, for metavanadate and decavanadate solutions, respectively),
being 80-fold higher than in RBC. After 12 h of administration, the amount of vanadium in plasma, as well as in cardiac cytosol, decreased about 50%, for both vanadate
solutions. During the period between 1 and 12 h, the ratio of vanadium in plasma/vanadium in RBC increased from 27 to
128 for metavanadate, whereas it r...
Background. HIV infected women have higher rates of infertility. Objective. The purpose of this literature review is to evaluate the effectiveness of fresh IVF/ICSI cycles in HIV infected women. Materials and Methods. A search of the PubMed database was performed to identify studies assessing fresh nondonor oocyte IVF/ICSI cycle outcomes of serodiscordant couples with an HIV infected female partner. Results and Discussion. Ten studies met the inclusion criteria. Whenever a comparison with a control group was available, with the exception of one case, ovarian stimulation cancelation rate was higher and pregnancy rate (PR) was lower in HIV infected women. However, statistically significant differences in both rates were only seen in one and two studies, respectively. A number of noncontrolled sources of bias for IVF outcome were identifi...
This descriptive scoping aims to understand how the prevalence of cyberbullying has been estimated across studies. A systematic scoping review of cyberbullying empirical studies was conducted by using three bibliographic databases to search for papers published between January 2004 and August 2014. A protocol was defined to identify the relevant papers. Papers selected were included in a data sheet developed by the authors to record specific findings. In total, 159 studies were included in the scoping review. Most of the prevalence studies were conducted in the last 4 years, mainly in North America (n = 77) and in Europe (n = 65). High methodological heterogeneity was found among the studies, which may contribute to explain variability in prevalence estimates. Cyberbullying experiences were assessed through several different perspectiv...
Essential Thrombocythemia (ET) is a rare disease in
pediatric age. The dominant clinical manifestations are thrombotic
(arterial or venous) and/or hemorrhagic, but most of the cases
are asymptomatic, and diagnosis made by routine hemogram.
A previously healthy adolescent, federated football player,
was oriented to the paediatric haematology consultation, at the
age of 15 years, because of the presence of sustained thrombocytosis.
It was established the diagnosis of Essential Thrombocythemia
based on the criteria of the World Health Organization (WHO) 2008.
The authors highlight the importance of establishing this
diagnosis, even in pediatric age, to set the earliest possible a
strategy of clinical surveillance, prevention of associated complications
and the most adequate therapeutic approach.
In a previous in vivo study we have reported that vanadium distribution, antioxidant enzymes activity and lipid peroxidation in Sparus aurata heart are strongly dependent on the oligomeric vanadate species being administered. Moreover, it was suggested that vanadium is accumulated in mitochondria, in particular when V10 was intravenously injected. In this work we have done a comparative study of the effects of V10 and monomeric vanadate (V1) on cardiac mitochondria from S. aurata. V10 inhibits mitochondrial oxygen consumption with an IC50 of 400 nM, while the IC50 for V1 is 23 M. V10 also induced mitochondrial depolarization at very low concentrations, with an IC50 of 196 nM, and 55 Mof V1was
required to induce the same effect. Additionally, up to 5 M V10 did inhibit neither F0F1-ATPase activity nor NADH levels and it did not affect...
